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    • EMDB
    • Computational Bioimaging
      • Particle picking using SVMs
      • Model-free classification of views
      • Extending Chimera
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      • Protein function
      • Soft clustering
      • Network inference
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I am a software engineer with Google's London office, where I work on problems involving large data and large computers.

For a long time, I used to be a computational theoretical physicist working in high-energy and nuclear physics, but my main interests now are in software engineering and computer science, as well as in advanced mathematical and statistical methods.

Until September 2010, I was a scientist at the European Bioinformatics Institute in Cambridge, UK, where I led the Electron Microscopy Data Bank project, a 3D image data base of molecular and sub-cellular structures. (Unfortunately, my role at EBI did not quite evolve the way I hoped, and when Google contacted me and made me an offer, I could not resist).

EMDB, the project I was working on, is an example of how computational science can contribute to life sciences. We were not only a central storage and exchange facility for the results of biological electron microscopy labs all over the world, we also provided standardized description and visualization of biological experimens, facilitated the definition of standards and best practices, and interacted closely with other bioimage informatics groups. In particular, we also did provide quality assessment using manual curation, and I hoped grid and cloud computing and storage would play a major role in the future when more automatic quality assessment algorithms become viable.

Before joining EBI, I was responsible for image processing and computing at the Department of Molecular Structural Biology of the Max Planck Institute for Biochemistry in Martinsried.

In previous lifes, I worked in bioinformatics and LMU Munich, in high-performance computing in Jülich/Aachen, in theoretical physics in Frankfurt and Boston, and in visualization in Berlin.

I hold a Dipl.-Phys. and a Ph.D. in Theoretical Physics from Johann Wolfgang Goethe University in Frankfurt.

2011-01-01 00:40 CET     xris